Hepatologie Neuere Forschungsergebnisse in ihrer Bedeutung für das Verständnis von Leberkrankheiten
Identifieur interne : 001156 ( Main/Exploration ); précédent : 001155; suivant : 001157Hepatologie Neuere Forschungsergebnisse in ihrer Bedeutung für das Verständnis von Leberkrankheiten
Auteurs : W. Gerok [Allemagne] ; E. Blum [Allemagne] ; W. Offensperger [Allemagne] ; S. Offensperger [Allemagne] ; T. Andus [Allemagne] ; V. Gro [Allemagne] ; C. Heinrich [Allemagne]Source :
- Naturwissenschaften [ 0028-1042 ] ; 1991-06-01.
Abstract
Abstract: By two exemplary clinical situations — acute viral hepatitis, acute-phase reaction of the liver — the significance of basic research for the understanding of clinical phenomena and for the development of new diagnostic and therapeutic procedures is demonstrated. The very different phenomena following infection with the hepatitis-B-virus can be explained by the variation in the interactions of virus and liver cell, by the immune reaction of the host, and by mutants of the virus. The reaction of the liver to an extrahepatic infection is mediated by interleukin-6, and characterized by an alteration in protein metabolism. The synthesis of acute-phase proteins is increased. The proteins confine the local injury and establish the homeostasis of the organism.
Url:
DOI: 10.1007/BF01134350
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="de">Hepatologie Neuere Forschungsergebnisse in ihrer Bedeutung für das Verständnis von Leberkrankheiten</title>
<author><name sortKey="Gerok, W" sort="Gerok, W" uniqKey="Gerok W" first="W." last="Gerok">W. Gerok</name>
</author>
<author><name sortKey="Blum, E" sort="Blum, E" uniqKey="Blum E" first="E." last="Blum">E. Blum</name>
</author>
<author><name sortKey="Offensperger, W" sort="Offensperger, W" uniqKey="Offensperger W" first="W." last="Offensperger">W. Offensperger</name>
</author>
<author><name sortKey="Offensperger, S" sort="Offensperger, S" uniqKey="Offensperger S" first="S." last="Offensperger">S. Offensperger</name>
</author>
<author><name sortKey="Andus, T" sort="Andus, T" uniqKey="Andus T" first="T." last="Andus">T. Andus</name>
</author>
<author><name sortKey="Gro, V" sort="Gro, V" uniqKey="Gro V" first="V." last="Gro">V. Gro</name>
</author>
<author><name sortKey="Heinrich, C" sort="Heinrich, C" uniqKey="Heinrich C" first="C." last="Heinrich">C. Heinrich</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:583AC247174BA5CB8F28A293444FFA18D975958E</idno>
<date when="1991" year="1991">1991</date>
<idno type="doi">10.1007/BF01134350</idno>
<idno type="url">https://api.istex.fr/document/583AC247174BA5CB8F28A293444FFA18D975958E/fulltext/pdf</idno>
<idno type="wicri:Area/Main/Corpus">000B93</idno>
<idno type="wicri:Area/Main/Curation">000B78</idno>
<idno type="wicri:Area/Main/Exploration">001156</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Exploration">001156</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="de">Hepatologie Neuere Forschungsergebnisse in ihrer Bedeutung für das Verständnis von Leberkrankheiten</title>
<author><name sortKey="Gerok, W" sort="Gerok, W" uniqKey="Gerok W" first="W." last="Gerok">W. Gerok</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Medizinische Universitätsklinik, W-7800, Freiburg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Fribourg-en-Brisgau</region>
<settlement type="city">Fribourg-en-Brisgau</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Blum, E" sort="Blum, E" uniqKey="Blum E" first="E." last="Blum">E. Blum</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Medizinische Universitätsklinik, W-7800, Freiburg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Fribourg-en-Brisgau</region>
<settlement type="city">Fribourg-en-Brisgau</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Offensperger, W" sort="Offensperger, W" uniqKey="Offensperger W" first="W." last="Offensperger">W. Offensperger</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Medizinische Universitätsklinik, W-7800, Freiburg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Fribourg-en-Brisgau</region>
<settlement type="city">Fribourg-en-Brisgau</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Offensperger, S" sort="Offensperger, S" uniqKey="Offensperger S" first="S." last="Offensperger">S. Offensperger</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Medizinische Universitätsklinik, W-7800, Freiburg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Fribourg-en-Brisgau</region>
<settlement type="city">Fribourg-en-Brisgau</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Andus, T" sort="Andus, T" uniqKey="Andus T" first="T." last="Andus">T. Andus</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Medizinische Universitätsklinik, W-7800, Freiburg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Fribourg-en-Brisgau</region>
<settlement type="city">Fribourg-en-Brisgau</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gro, V" sort="Gro, V" uniqKey="Gro V" first="V." last="Gro">V. Gro</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Medizinische Universitätsklinik, W-7800, Freiburg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Fribourg-en-Brisgau</region>
<settlement type="city">Fribourg-en-Brisgau</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Heinrich, C" sort="Heinrich, C" uniqKey="Heinrich C" first="C." last="Heinrich">C. Heinrich</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Medizinische Universitätsklinik, W-7800, Freiburg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Fribourg-en-Brisgau</region>
<settlement type="city">Fribourg-en-Brisgau</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Naturwissenschaften</title>
<title level="j" type="abbrev">Naturwissenschaften</title>
<idno type="ISSN">0028-1042</idno>
<idno type="eISSN">1432-1904</idno>
<imprint><publisher>Springer-Verlag</publisher>
<pubPlace>Berlin/Heidelberg</pubPlace>
<date type="published" when="1991-06-01">1991-06-01</date>
<biblScope unit="volume">78</biblScope>
<biblScope unit="issue">6</biblScope>
<biblScope unit="page" from="241">241</biblScope>
<biblScope unit="page" to="249">249</biblScope>
</imprint>
<idno type="ISSN">0028-1042</idno>
</series>
<idno type="istex">583AC247174BA5CB8F28A293444FFA18D975958E</idno>
<idno type="DOI">10.1007/BF01134350</idno>
<idno type="ArticleID">Art1</idno>
<idno type="ArticleID">BF01134350</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0028-1042</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass></textClass>
<langUsage><language ident="de">de</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Abstract: By two exemplary clinical situations — acute viral hepatitis, acute-phase reaction of the liver — the significance of basic research for the understanding of clinical phenomena and for the development of new diagnostic and therapeutic procedures is demonstrated. The very different phenomena following infection with the hepatitis-B-virus can be explained by the variation in the interactions of virus and liver cell, by the immune reaction of the host, and by mutants of the virus. The reaction of the liver to an extrahepatic infection is mediated by interleukin-6, and characterized by an alteration in protein metabolism. The synthesis of acute-phase proteins is increased. The proteins confine the local injury and establish the homeostasis of the organism.</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
</country>
<region><li>Bade-Wurtemberg</li>
<li>District de Fribourg-en-Brisgau</li>
</region>
<settlement><li>Fribourg-en-Brisgau</li>
</settlement>
</list>
<tree><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Gerok, W" sort="Gerok, W" uniqKey="Gerok W" first="W." last="Gerok">W. Gerok</name>
</region>
<name sortKey="Andus, T" sort="Andus, T" uniqKey="Andus T" first="T." last="Andus">T. Andus</name>
<name sortKey="Blum, E" sort="Blum, E" uniqKey="Blum E" first="E." last="Blum">E. Blum</name>
<name sortKey="Gro, V" sort="Gro, V" uniqKey="Gro V" first="V." last="Gro">V. Gro</name>
<name sortKey="Heinrich, C" sort="Heinrich, C" uniqKey="Heinrich C" first="C." last="Heinrich">C. Heinrich</name>
<name sortKey="Offensperger, S" sort="Offensperger, S" uniqKey="Offensperger S" first="S." last="Offensperger">S. Offensperger</name>
<name sortKey="Offensperger, W" sort="Offensperger, W" uniqKey="Offensperger W" first="W." last="Offensperger">W. Offensperger</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Musique/explor/SchutzV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001156 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001156 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Musique |area= SchutzV1 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:583AC247174BA5CB8F28A293444FFA18D975958E |texte= Hepatologie Neuere Forschungsergebnisse in ihrer Bedeutung für das Verständnis von Leberkrankheiten }}
This area was generated with Dilib version V0.6.38. |